article Open AccessTop 1% cited
Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment
Neurology · 1999 · Vol. 52(7) · pp. 1397–1397
Clifford R. Jack✉(Mayo Clinic)Ronald Petersen(Mayo Clinic)Yun Xu(Mayo Clinic)Peter C. O’Brien(Mayo Clinic)Glenn E. Smith(Mayo Clinic)Robert J. Ivnik(Mayo Clinic)Bradley F. Boeve(Mayo Clinic)Stephen C. Waring(Mayo Clinic)Eric G. Tangalos(Mayo Clinic)E. Kokmen(Mayo Clinic)
Abstract
In older patients with MCI, hippocampal atrophy determined by premorbid MRI-based volume measurements is predictive of subsequent conversion to AD.
Dementia and Cognitive Impairment ResearchFunctional Brain Connectivity StudiesNeurological Disease Mechanisms and TreatmentsCognitive impairmentHippocampal formationMedicineNeuroscienceVolume (thermodynamics)Brain sizeMagnetic resonance imagingCognitionPsychologyInternal medicine
MeSH terms
AgedAged, 80 and overAgingAlzheimer DiseaseApolipoproteins ECognition DisordersHippocampusHumansHypertensionMagnetic Resonance ImagingMiddle AgedPredictive Value of TestsEstrogen Replacement TherapySurvival AnalysisMyocardial Ischemia
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