article Open AccessTop 1% cited
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
Nature Cell Biology · 2011 · Vol. 13(9) · pp. 1016–1023
Maria M. Mihaylova✉(Salk Institute for Biological Studies)Reuben J. Shaw(Howard Hughes Medical Institute)
Metabolism, Diabetes, and CancerAutophagy in Disease and TherapyPancreatic function and diabetesAMPKAutophagyCell biologyEffectorAMP-activated protein kinaseProtein kinase AIntracellularCell metabolismKinaseMetabolism
MeSH terms
AnimalsAutophagyHumansModels, BiologicalSignal TransductionCell PolarityProtein SubunitsCell ProliferationAMP-Activated Protein KinasesEukaryota
Funding
- Howard Hughes Medical Institute
- American Diabetes Association
- American Cancer Society
- Leona M. and Harry B. Helmsley Charitable Trust
- National Institutes of Health
Citations
2,884
FWCI
47.64
field-weighted impact
References
134
Percentile
100%
vs. same field & year
Citations per year
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References
AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome
Cell Metabolism · 2009 · 1,029 citations
Eaten alive: a history of macroautophagy
Nature Cell Biology · 2010 · 2,075 citations
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
Cell Metabolism · 2005 · 2,787 citations
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Nature Cell Biology · 2011 · 6,906 citations
LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade
Current Biology · 2003 · 1,631 citations
AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
Cell Metabolism · 2011 · 1,713 citations
SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
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Current Opinion in Cell Biology · 2010 · 1,050 citations
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