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Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13

Bioorganic & Medicinal Chemistry Letters · 2012 · Vol. 22(12) · pp. 4049–4054
Mi-Sun YuJune LeeJin‐Moo LeeYoung-Gyu KimYoung‐Won ChinJun‐Goo JeeYoung‐Sam KeumYong‐Joo Jeong
Computational Drug Discovery MethodsPharmacological Effects of Natural Compoundsthermodynamics and calorimetric analysesMyricetinHelicaseChemistryATP hydrolysisBiochemistryATPaseCoronavirusMolecular biologyEnzymeFlavonoid

MeSH terms

Adenosine TriphosphateAntiviral AgentsBreastCell LineColorimetryDNADNA HelicasesEpithelial CellsFemaleFlavonoidsHumansHydrolysisKineticsMethyltransferasesSpecies Specificity

Funding

  • National Research Foundation
  • Kookmin University
  • National Research Foundation of Korea
  • Ministry of Education, Science and Technology
Citations
426
FWCI
5.58
field-weighted impact
References
9
Percentile
96%
vs. same field & year
Citations per year
References
SARS: Systematic Review of Treatment Effects
PLoS Medicine · 2006 · 1,268 citations
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