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Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer

British journal of surgery · 2012 · Vol. 99(7) · pp. 918–928
Seán MartinHelen HeneghanD. C. Winter

Abstract

A pCR following neoadjuvant CRT is associated with excellent long-term survival, with low rates of local recurrence and distant failure.

Colorectal Cancer Surgical TreatmentsColorectal and Anal CarcinomasColorectal Cancer Screening and DetectionMedicineNeoadjuvant therapyMeta-analysisColorectal cancerOdds ratioInternal medicineChemoradiotherapyCochrane LibraryConfidence intervalSurgery

MeSH terms

AdenocarcinomaAntimetabolites, AntineoplasticFemaleFluorouracilHumansMaleMiddle AgedRectal NeoplasmsTreatment OutcomeDisease-Free SurvivalNeoadjuvant TherapyChemoradiotherapy
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