reviewTop 1% cited
Sorafenib
Drugs · 2009 · Vol. 69(2) · pp. 223–240
Gillian M. Keating✉(Wolters Kluwer Health)Armando Santoro(Fondazione Humanitas per la Ricerca)
Hepatocellular Carcinoma Treatment and PrognosisPI3K/AKT/mTOR signaling in cancerCancer Mechanisms and TherapySorafenibHepatocellular carcinomaMedicineCancer researchPharmacologyAngiogenesisVascular endothelial growth factorTyrosine-kinase inhibitorInternal medicineOncology
MeSH terms
SorafenibAnimalsAntineoplastic AgentsBenzenesulfonatesDrug InteractionsCarcinoma, HepatocellularHumansLiver NeoplasmsNiacinamidePhenylurea CompoundsPyridinesProtein Kinase Inhibitors
Citations
483
FWCI
13.53
field-weighted impact
References
31
Percentile
99%
vs. same field & year
Citations per year
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References
Sorafenib in Advanced Hepatocellular Carcinoma
New England Journal of Medicine · 2008 · 12,835 citations
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
The Lancet Oncology · 2008 · 5,801 citations
Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
Nature Reviews Drug Discovery · 2006 · 1,812 citations
Sorafenib Blocks the RAF/MEK/ERK Pathway, Inhibits Tumor Angiogenesis, and Induces Tumor Cell Apoptosis in Hepatocellular Carcinoma Model PLC/PRF/5
Cancer Research · 2006 · 1,531 citations
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
Gastroenterology · 2007 · 5,410 citations
BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis
Cancer Research · 2004 · 4,006 citations
Design and Endpoints of Clinical Trials in Hepatocellular Carcinoma
JNCI Journal of the National Cancer Institute · 2008 · 1,656 citations
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