articleTop 1% cited
Trial sequential analysis reveals insufficient information size and potentially false positive results in many meta-analyses
Journal of Clinical Epidemiology · 2008 · Vol. 61(8) · pp. 763–769
Jesper Brok✉(Copenhagen University Hospital)Kristian Thorlund(Cochrane)Christian Gluud(Copenhagen University Hospital)Jørn Wetterslev(Copenhagen University Hospital)
Meta-analysis and systematic reviewsHemodynamic Monitoring and TherapyStatistical Methods in Clinical TrialsMeta-analysisMedicineMEDLINEStatisticsInternal medicineMathematicsBiology
MeSH terms
Data Interpretation, StatisticalFalse Positive ReactionsHumansInfant, NewbornResearch DesignReview Literature as TopicMeta-Analysis as TopicRandomized Controlled Trials as TopicSample Size
Citations
1,153
FWCI
29.47
field-weighted impact
References
43
Percentile
100%
vs. same field & year
Citations per year
Cited by
Psychological therapies for people with borderline personality disorder
Cochrane Database of Systematic Reviews · 2012 · 905 citations
Antenatal magnesium sulphate may prevent cerebral palsy in preterm infants-but are we convinced? Evaluation of an apparently conclusive meta-analysis with trial sequential analysis
BJOG An International Journal of Obstetrics & Gynaecology · 2010 · 533 citations
Apparently conclusive meta-analyses may be inconclusive—Trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses
International Journal of Epidemiology · 2008 · 946 citations
Urban natural environments as nature-based solutions for improved public health – A systematic review of reviews
Environmental Research · 2017 · 924 citations
References
Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis
Journal of Clinical Epidemiology · 2007 · 1,856 citations
Discrete sequential boundaries for clinical trials
Biometrika · 1983 · 1,735 citations
Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials
JAMA · 1995 · 5,583 citations
Methods for combining randomized clinical trials: Strengths and limitations
Statistics in Medicine · 1987 · 1,047 citations
Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses?
International Journal of Epidemiology · 2008 · 858 citations
Reported Methodologic Quality and Discrepancies between Large and Small Randomized Trials in Meta-Analyses
Annals of Internal Medicine · 2001 · 2,318 citations
Quantifying heterogeneity in a meta‐analysis
Statistics in Medicine · 2002 · 36,106 citations
Group sequential methods in the design and analysis of clinical trials
Biometrika · 1977 · 1,771 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.