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The Quantitative Measurement of DNA Hybridization from Renaturation Rates
European Journal of Biochemistry · 1970 · Vol. 12(1) · pp. 133–142
Abstract
A new method is proposed to measure relatedness amongst bacteria, based on renaturation rate determinations of DNA types and their mixture. The equations, relating the degree of binding with renaturation rates, are calculated for several cases. The optimal conditions for measurements are given. The method was checked in several ways. The advantages are summarized.
DNA and Nucleic Acid ChemistryEnterobacteriaceae and Cronobacter ResearchDNA Repair MechanismsDNADNA–DNA hybridizationMeasure (data warehouse)Similarity (geometry)BiologyChemistryBiological systemComputational biologyGeneticsComputer science
MeSH terms
Bacillus subtilisBacteriaCarbon IsotopesChemistryChromosomesCulture MediaDNA, BacterialDrug StabilityEscherichia coliFiltrationMathematicsMembranes, ArtificialMethodsMolecular WeightNucleic Acid Denaturation
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Journal of Molecular Biology · 1965 · 1,971 citations
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