reviewTop 1% cited
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
Trends in Biochemical Sciences · 2014 · Vol. 39(4) · pp. 199–218
John D. Hayes✉(University of Dundee)Albena T. Dinkova‐Kostova(University of Dundee)
Genomics, phytochemicals, and oxidative stressAdipose Tissue and MetabolismGlutathione Transferases and PolymorphismsTranscription factorCell biologyBiologyPentose phosphate pathwayChemistryBiochemistryMetabolismGeneGlycolysis
MeSH terms
Gene Expression RegulationHumansMitochondriaOxidation-ReductionLipid MetabolismNF-E2-Related Factor 2Metabolic Networks and Pathways
Citations
2,052
FWCI
57.66
field-weighted impact
References
179
Percentile
100%
vs. same field & year
Citations per year
Cited by
Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling
Stem Cells · 2016 · 531 citations
NRF2, a Transcription Factor for Stress Response and Beyond
International Journal of Molecular Sciences · 2020 · 1,614 citations
Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment
Cancer Letters · 2017 · 569 citations
NRF2 and the Hallmarks of Cancer
Cancer Cell · 2018 · 1,592 citations
The emerging role of Nrf2 in mitochondrial function
Free Radical Biology and Medicine · 2015 · 945 citations
Reactive oxygen species and fibrosis: further evidence of a significant liaison
Cell and Tissue Research · 2016 · 320 citations
Oxidative Stress in Cancer
Cancer Cell · 2020 · 2,420 citations
Molecular basis of the Keap1–Nrf2 system
Free Radical Biology and Medicine · 2015 · 973 citations
References
NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
Trends in Biochemical Sciences · 2009 · 863 citations
The thioredoxin antioxidant system
Free Radical Biology and Medicine · 2013 · 1,975 citations
An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements
Biochemical and Biophysical Research Communications · 1997 · 3,915 citations
The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism
Frontiers in Oncology · 2012 · 384 citations
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Cancer Cell · 2012 · 1,350 citations
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Science · 2009 · 15,796 citations
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
Nature Cell Biology · 2010 · 2,361 citations
Fibroblast Growth Factor 21 Corrects Obesity in Mice
Endocrinology · 2008 · 1,010 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
