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Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: A review

Toxicology and Applied Pharmacology · 2005 · Vol. 206(1) · pp. 73–93
Weiling XueDavid Warshawsky
Bioactive Compounds and Antitumor AgentsFree Radicals and AntioxidantsGenomics, phytochemicals, and oxidative stressChemistryCarcinogenMetabolic pathwayDNA damageReactive intermediateBiochemistryAdductCYP1A2Cytochrome P450DNA

MeSH terms

AnimalsBiotransformationCarcinogensEpoxy CompoundsHeterocyclic CompoundsPolycyclic Aromatic HydrocarbonsStereoisomerismStructure-Activity RelationshipDNA Adducts

Funding

  • National Institute of Environmental Health Sciences
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