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Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver

Biochemical Pharmacology · 1994 · Vol. 48(5) · pp. 923–936

M.D. Burke✉(University of Aberdeen)S. Thompson(University of Aberdeen)Richard Weaver(University of Aberdeen)C. Roland Wolf(Ninewells Hospital)Richard T. Mayers(U.S. Horticultural Research Laboratory)

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Pharmacogenetics and Drug Metabolism Drug Transport and Resistance Mechanisms Inflammatory mediators and NSAID effectsHuman liverCytochrome P450AlkylationBiochemistryChemistryBiologyStereochemistryEnzyme

MeSH terms

AdultAlkylationAnimalsChromatography, High Pressure LiquidCytochrome P-450 Enzyme SystemHumansIsoenzymesMaleMicrosomes, LiverMiddle AgedOxazinesOxidoreductasesSpecies SpecificitySubstrate SpecificityTheophylline

Citations

553

FWCI

13.17

field-weighted impact

References

Percentile

99%

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Citations per year

References

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

Biochemical Pharmacology · 1985 · 1,274 citations

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

Biochemistry · 1982 · 1,017 citations

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