articleTop 1% cited

Molecular Beacons: Probes that Fluoresce upon Hybridization

Nature Biotechnology · 1996 · Vol. 14(3) · pp. 303–308

Sanjay Tyagi✉(New York Institute of Technology)Fred Russell Kramer

Advanced biosensing and bioanalysis techniques DNA and Nucleic Acid Chemistry Bacteriophages and microbial interactionsMolecular beaconNucleic acidMolecular probeHomogeneousNucleic acid thermodynamicsNucleic acid detectionHybridization probeNucleic acid quantitationBiologyLocked nucleic acid

MeSH terms

Base SequenceBiotechnologyp-DimethylaminoazobenzeneFluorescent DyesNaphthalenesulfonatesNucleic Acid HybridizationMolecular ProbesMolecular StructurePolymerase Chain ReactionDNA Primers

Citations

4,141

FWCI

13.32

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99%

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References

Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization.

Genome Research · 1995 · 1,606 citations

Kinetic PCR Analysis: Real-time Monitoring of DNA Amplification Reactions

Nature Biotechnology · 1993 · 2,161 citations

Fluorescence Energy Transfer as a Spectroscopic Ruler

Annual Review of Biochemistry · 1978 · 2,395 citations

Molecular Beacons: Probes that Fluoresce upon Hybridization

Nature Biotechnology · 1996 · 4,141 citations

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