articleTop 10% cited

β-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies

Biochemical Pharmacology · 2003 · Vol. 65(3) · pp. 407–416

Manuela Bartolini(University of Bologna)Carlo Bertucci(University of Bologna)Vanni Cavrini(University of Bologna)Vincenza Andrisano✉(University of Bologna)

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Cholinesterase and Neurodegenerative Diseases Alzheimer's disease research and treatments Computational Drug Discovery MethodsThioflavinDecamethoniumChemistryCircular dichroismAcetylcholinesteraseTacrineBiophysicsPhysostigmineHuperzine AFluorescence

MeSH terms

AcetylcholinesteraseCholinesterase InhibitorsCircular DichroismFluorometryHumansPeptide FragmentsProtein ConformationRecombinant ProteinsAmyloid beta-Peptides

Funding

Università di Bologna

Citations

564

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10.81

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99%

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Cited by

Multi-target-Directed Ligands To Combat Neurodegenerative Diseases

Journal of Medicinal Chemistry · 2008 · 1,103 citations

References

A new and rapid colorimetric determination of acetylcholinesterase activity

Biochemical Pharmacology · 1961 · 26,665 citations

Thioflavine T interaction with synthetic Alzheimer's disease <i>β</i>‐amyloid peptides: Detection of amyloid aggregation in solution

Protein Science · 1993 · 2,237 citations

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