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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
Cancer Cell · 2006 · Vol. 9(5) · pp. 391–403
Jeongwu Lee(National Institute of Neurological Disorders and Stroke)Svetlana Kotliarova(National Institutes of Health)Yuri Kotliarov(National Institutes of Health)Aiguo Li(National Institutes of Health)Qin Su(National Institutes of Health)Nicholas M. Donin(National Institutes of Health)Sandra Pastorino(National Institutes of Health)Benjamin Purow(National Institutes of Health)Neil Christopher(National Institutes of Health)Wei Zhang(National Institutes of Health)John K. Park(National Institutes of Health)Howard A. Fine✉(National Institutes of Health)
Cancer Cells and MetastasisGlioma Diagnosis and TreatmentMicroRNA in disease regulationBiologyPhenotypeCell cultureGenotypeCancer stem cellStem cellCancer researchGliomaImmunologyGene
MeSH terms
AnimalsEpidermal Growth FactorGenotypeGlioblastomaHumansModels, BiologicalPhenotypeTranscription, GeneticTumor Cells, CulturedNeoplastic Stem CellsGenome, HumanCluster AnalysisFibroblast Growth Factor 2Mice, SCIDLoss of Heterozygosity
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References
Cancer genes and the pathways they control
Nature Medicine · 2004 · 4,243 citations
Tumour stem cells and drug resistance
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Stem cells, cancer, and cancer stem cells
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