review Open AccessTop 1% cited
AMPK: a nutrient and energy sensor that maintains energy homeostasis
Nature Reviews Molecular Cell Biology · 2012 · Vol. 13(4) · pp. 251–262
D. Grahame Hardie✉(University of Dundee)Fiona A. Ross(University of Dundee)Simon A. Hawley(University of Dundee)
Metabolism, Diabetes, and CancerPancreatic function and diabetesAdipose Tissue and MetabolismAMPKEnergy homeostasisCell biologyCatabolismProtein kinase AAMP-activated protein kinaseHomeostasisIntracellularChemistryMetabolism
MeSH terms
Adenosine DiphosphateAdenosine TriphosphateAnimalsAppetiteCircadian RhythmEnergy MetabolismGlucoseHumansHypothalamusMammalsMitochondriaXenobioticsOxidative StressGlucose Transporter Type 4AMP-Activated Protein Kinases
Funding
- Wellcome Trust
Citations
4,338
FWCI
109.27
field-weighted impact
References
125
Percentile
100%
vs. same field & year
Citations per year
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References
Metabolic control through the PGC-1 family of transcription coactivators
Cell Metabolism · 2005 · 2,105 citations
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Nature Cell Biology · 2011 · 6,906 citations
LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade
Current Biology · 2003 · 1,631 citations
AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
Cell Metabolism · 2011 · 1,713 citations
An Energy Budget for Signaling in the Grey Matter of the Brain
Journal of Cerebral Blood Flow & Metabolism · 2001 · 3,449 citations
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
Cell Metabolism · 2005 · 1,557 citations
AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
Molecular Cell · 2008 · 3,735 citations
Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
Cell Metabolism · 2005 · 1,371 citations
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