article Open AccessTop 1% cited
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
Cell Metabolism · 2005 · Vol. 2(1) · pp. 9–19
Simon A. Hawley(University of Dundee)David Pan(University of Dundee)Kirsty J. Mustard(University of Dundee)Louise C. Ross(University of Dundee)Jenny Bain(University of Dundee)Arthur Edelman(University at Buffalo, State University of New York)Bruno G. Frenguelli(University of Dundee)D. Grahame Hardie✉(University of Dundee)
Metabolism, Diabetes, and CancerPancreatic function and diabetesPlant nutrient uptake and metabolismAMPKProtein kinase AAMP-activated protein kinaseCell biologyKinaseMitogen-activated protein kinase kinaseCyclin-dependent kinase 2PhosphorylationBiologyMAP2K7
MeSH terms
CalcimycinAcetyl-CoA CarboxylaseAdenosine DiphosphateAdenosine TriphosphateAnimalsBenzimidazolesBrainEnzyme ActivationFibroblastsHeLa CellsHumansIsoquinolinesMultienzyme ComplexesPhosphoprotein PhosphatasesPhosphorylation
Citations
1,557
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27.87
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References
52
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100%
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References
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
Cell Metabolism · 2005 · 2,787 citations
Management of cellular energy by the AMP‐activated protein kinase system
FEBS Letters · 2003 · 855 citations
LKB1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade
Current Biology · 2003 · 1,631 citations
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
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The specificities of protein kinase inhibitors: an update
Biochemical Journal · 2003 · 1,355 citations
The AMP-activated protein kinase pathway – new players upstream and downstream
Journal of Cell Science · 2004 · 1,135 citations
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
The EMBO Journal · 2004 · 1,359 citations
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