articleTop 1% cited
The molecular biology of chronic myeloid leukemia
Blood · 2000 · Vol. 96(10) · pp. 3343–3356
Michael W. Deininger✉(Hammersmith Hospital)John M. Goldman(Hammersmith Hospital)Junia V. Melo(Hammersmith Hospital)
Abstract
Chronic myeloid leukemia (CML) is probably the most extensively studied human malignancy. The discovery of the Philadelphia (Ph) chromosome in 19601 as the first consistent chromosomal abnormality associated with a specific type of leukemia was a breakthrough in cancer biology. It took 13 years
Chronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia ResearchLymphoma Diagnosis and TreatmentMyeloid leukemiaBiologyLeukemiaChronic lymphocytic leukemiaMyeloidImmunologyCancer researchComputational biology
MeSH terms
AnimalsHumansPhiladelphia ChromosomeProtein-Tyrosine KinasesSignal TransductionLeukemia, Myelogenous, Chronic, BCR-ABL PositiveGenes, abl
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References
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells
Nature Medicine · 1996 · 3,643 citations
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