articleTop 1% cited
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells
Nature Medicine · 1996 · Vol. 2(5) · pp. 561–566
Brian Druker✉(Oregon Health & Science University)Shu Tamura(Oregon Health & Science University)Elisabeth Buchdunger(Novartis (Switzerland))Sayuri Ohno(Oregon Health & Science University)Gerald M. Segal(Oregon Health & Science University)Shane Fanning(Oregon Health & Science University)J. Zimmermann(Novartis (Switzerland))Nicholas Lydon(Novartis (Switzerland))
Chronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia ResearchEosinophilic Disorders and SyndromesChronic myelogenous leukemiaABLTyrosine kinaseCancer researchFusion proteinbreakpoint cluster regionPhiladelphia chromosomeCD135LeukemiaTyrosine-kinase inhibitor
MeSH terms
Imatinib MesylateAnimalsBenzamidesBlood CellsBone MarrowDose-Response Relationship, DrugEnzyme InhibitorsEvaluation Studies as TopicHumansPiperazinesProtein-Tyrosine KinasesPyrimidinesStem CellsTumor Cells, CulturedLeukemia, Myelogenous, Chronic, BCR-ABL Positive
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3,643
FWCI
12.74
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References
52
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99%
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References
Multiple Comparisons Using Rank Sums
Technometrics · 1964 · 4,260 citations
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
Journal of Immunological Methods · 1983 · 55,054 citations
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