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Regulation of angiogenesis by hypoxia: role of the HIF system

Nature Medicine · 2003 · Vol. 9(6) · pp. 677–684
Christopher W. PughPeter J. Ratcliffe
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in CancerCancer, Lipids, and MetabolismAngiogenesisRegulatorHypoxia (environmental)Hypoxia-inducible factorsBiologyCell biologyPhenotypeHIF1ASignal transductionTranscription factor

MeSH terms

AnimalsHypoxiaDNA-Binding ProteinsHumansHydroxylationNeoplasmsNeovascularization, PathologicNuclear ProteinsTranscription FactorsGene Expression Regulation, DevelopmentalNeovascularization, PhysiologicProtein IsoformsProtein SubunitsHypoxia-Inducible Factor 1Hypoxia-Inducible Factor 1, alpha Subunit
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