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Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease

Pharmacology Biochemistry and Behavior · 2008 · Vol. 91(4) · pp. 554–559
Touqeer AhmedAnwarul Hassan Gilani
Curcumin's Biomedical ApplicationsCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsCurcuminAcetylcholinesteraseAchéMorris water navigation taskAmnesiaIn vivoChemistryPharmacologyEx vivoTacrine

MeSH terms

AcetylcholinesteraseAlzheimer DiseaseAmnesiaAnimalsCholinesterase InhibitorsCurcuminDose-Response Relationship, DrugHippocampusMalePhytotherapyMemoryParasympatholyticsScopolamineRats, Sprague-DawleyPrefrontal Cortex

Funding

  • National Council for Higher Education
  • Yükseköğretim Kurulu
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Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease · Scinovex