article Open AccessTop 1% cited
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
Cell stem cell · 2010 · Vol. 7(3) · pp. 403–417
Gemma Molyneux✉(Institute of Cancer Research)Felipe C. Geyer(Institute of Cancer Research)Fiona‐Ann Magnay(Institute of Cancer Research)Afshan McCarthy(Institute of Cancer Research)Howard Kendrick(Institute of Cancer Research)Rachael Natrajan(Institute of Cancer Research)Alan Mackay(Institute of Cancer Research)Anita Grigoriadis(Guy's Hospital)Andrew Tutt(Guy's Hospital)Alan Ashworth(Institute of Cancer Research)Jorge S. Reis‐Filho(Institute of Cancer Research)Matthew J. Smalley(Institute of Cancer Research)
BRCA gene mutations in cancerGenomics and Chromatin DynamicsCancer Genomics and DiagnosticsBiologyBasal (medicine)Progenitor cellStem cellPhenocopyBreast cancerPhenotypeProgenitorHistogenesisKeratin 5
MeSH terms
AnimalsBreast NeoplasmsEpithelial CellsHumansPhenotypeStem CellsGenes, BRCA1Mice
Funding
- National Institute for Health and Care Research
Citations
803
FWCI
39.95
field-weighted impact
References
49
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100%
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Cited by
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References
The molecular portraits of breast tumors are conserved across microarray platforms
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Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
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Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma
Clinical Cancer Research · 2004 · 2,652 citations
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Proceedings of the National Academy of Sciences · 2005 · 55,472 citations
Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes
Journal of Clinical Oncology · 2009 · 4,815 citations
Repeated observation of breast tumor subtypes in independent gene expression data sets
Proceedings of the National Academy of Sciences · 2003 · 5,398 citations
A Gene-Expression Signature as a Predictor of Survival in Breast Cancer
New England Journal of Medicine · 2002 · 6,503 citations
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