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BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

Cell stem cell · 2010 · Vol. 7(3) · pp. 403–417
Gemma MolyneuxFelipe C. GeyerFiona‐Ann MagnayAfshan McCarthyHoward KendrickRachael NatrajanAlan MackayAnita GrigoriadisAndrew TuttAlan AshworthJorge S. Reis‐FilhoMatthew J. Smalley
BRCA gene mutations in cancerGenomics and Chromatin DynamicsCancer Genomics and DiagnosticsBiologyBasal (medicine)Progenitor cellStem cellPhenocopyBreast cancerPhenotypeProgenitorHistogenesisKeratin 5

MeSH terms

AnimalsBreast NeoplasmsEpithelial CellsHumansPhenotypeStem CellsGenes, BRCA1Mice

Funding

  • National Institute for Health and Care Research
Citations
803
FWCI
39.95
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References
49
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100%
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Cited by
The molecular pathology of breast cancer progression
The Journal of Pathology · 2010 · 463 citations
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