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Cardiovascular prevention and blood pressure reduction
Journal of Hypertension · 2003 · Vol. 21(6) · pp. 1055–1076
Abstract
The hypothesis that new antihypertensive drugs, such as calcium-channel blockers, alpha-blockers, ACE inhibitors or AR1 blockers might influence cardiovascular prognosis over and beyond their antihypertensive effects remains unproven. The finding that blood pressure differences largely accounted for cardiovascular outcome emphasizes the desirability of tight blood pressure control. However, the level to which blood pressure must be lowered to achieve maximal benefit remains currently unknown.
Blood Pressure and Hypertension StudiesHormonal Regulation and HypertensionRenin-Angiotensin System StudiesMedicineBlood pressureMyocardial infarctionInternal medicineCardiologyStroke (engine)Odds ratioClinical trialVerapamilRandomized controlled trial
MeSH terms
Antihypertensive AgentsHeart DiseasesHumansHypertensionRandomized Controlled Trials as TopicStroke
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References
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The Lancet · 2002 · 10,173 citations
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Journal of Hypertension · 2002 · 395 citations
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Journal of Hypertension · 2003 · 1,408 citations
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Journal of Hypertension · 1987 · 467 citations
Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes
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Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy
New England Journal of Medicine · 2001 · 7,433 citations
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