article Open AccessTop 1% cited
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
The EMBO Journal · 2001 · Vol. 20(23) · pp. 6877–6888
Sayda M. Elbashir✉(Max Planck Institute for Biophysical Chemistry)
RNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesSilk-based biomaterials and applicationsBiologyDrosophila melanogasterLibrary scienceBiochemistryComputer scienceGene
MeSH terms
AnimalsBase SequenceDrosophila melanogasterMolecular Sequence DataRNARNA Processing, Post-TranscriptionalRNA, BacterialOligonucleotides, AntisenseGene TargetingGene SilencingRNA, UntranslatedRNA, Small Interfering
Funding
- Bundesministerium für Bildung und Forschung
Citations
1,446
FWCI
36.34
field-weighted impact
References
50
Percentile
100%
vs. same field & year
Citations per year
Cited by
The Micro-Ribonucleic Acid (miRNA) miR-206 Targets the Human Estrogen Receptor-α (ERα) and Represses ERα Messenger RNA and Protein Expression in Breast Cancer Cell Lines
Molecular Endocrinology · 2007 · 479 citations
Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs
Molecular Cell · 2004 · 1,934 citations
Expression profiling reveals off-target gene regulation by RNAi
Nature Biotechnology · 2003 · 2,360 citations
Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells
Bioorganic & Medicinal Chemistry Letters · 2004 · 333 citations
Natural RNA circles function as efficient microRNA sponges
Nature · 2013 · 8,387 citations
Control of translation and mRNA degradation by miRNAs and siRNAs: Table 1.
Genes & Development · 2006 · 2,001 citations
Specific Effects of MicroRNAs on the Plant Transcriptome
Developmental Cell · 2005 · 1,477 citations
Purified Argonaute2 and an siRNA form recombinant human RISC
Nature Structural & Molecular Biology · 2005 · 773 citations
References
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
Nature · 2001 · 9,337 citations
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Nature · 1998 · 15,183 citations
RNA-triggered gene silencing
Trends in Genetics · 1999 · 619 citations
HOW CELLS RESPOND TO INTERFERONS
Annual Review of Biochemistry · 1998 · 3,942 citations
RNA silencing as a plant immune system against viruses
Trends in Genetics · 2001 · 738 citations
The lin-4 Regulatory RNA Controls Developmental Timing in Caenorhabditis elegans by Blocking LIN-14 Protein Synthesis after the Initiation of Translation
Developmental Biology · 1999 · 1,162 citations
RNA interference is mediated by 21- and 22-nucleotide RNAs
Genes & Development · 2001 · 3,295 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.