reviewTop 1% cited
Apoptosis: controlled demolition at the cellular level
Nature Reviews Molecular Cell Biology · 2007 · Vol. 9(3) · pp. 231–241
Rebecca C. Taylor✉(Trinity College Dublin)Sean P. Cullen(Trinity College Dublin)Séamus J. Martin(Trinity College Dublin)
Phagocytosis and Immune RegulationCell death mechanisms and regulationRNA Interference and Gene DeliveryProteasesProteolysisApoptosisCell biologyCaspaseProgrammed cell deathDemolitionImmune systemXIAPAutophagy
MeSH terms
AnimalsEnzyme ActivationHumansPhagocytesApoptosisCaspases
Funding
- Science Foundation Ireland
Citations
2,557
FWCI
31.26
field-weighted impact
References
106
Percentile
100%
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References
Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
The Journal of Immunology · 1992 · 3,312 citations
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
Cancer Cell · 2002 · 1,634 citations
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
British Journal of Cancer · 1972 · 15,557 citations
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Journal of Clinical Investigation · 1998 · 3,128 citations
Caspase structure, proteolytic substrates, and function during apoptotic cell death
Cell Death and Differentiation · 1999 · 1,540 citations
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
Nature Cell Biology · 2001 · 1,271 citations
The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis
Developmental Cell · 2001 · 1,723 citations
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.
The Journal of Experimental Medicine · 1995 · 2,850 citations
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