article Open AccessTop 1% cited
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
Cell stem cell · 2010 · Vol. 7(3) · pp. 380–390
Tugba Simsek✉(Southwestern Medical Center)Fatih Kocabaş(The University of Texas Southwestern Medical Center)Junke Zheng(Southwestern Medical Center)Ralph J. DeBerardinis(The University of Texas Southwestern Medical Center)Ahmed I. Mahmoud(The University of Texas Southwestern Medical Center)Eric N. Olson(Southwestern Medical Center)Jay W. Schneider(Southwestern Medical Center)Cheng Zhang(Southwestern Medical Center)Hesham A. Sadek(Southwestern Medical Center)
Cancer, Hypoxia, and MetabolismHematopoietic Stem Cell TransplantationImmune cells in cancerBiologyHaematopoiesisStem cellCell biologyOxidative phosphorylationBone marrowProgenitor cellGlycolysisTransplantationHematopoietic stem cell
MeSH terms
Myeloid Ecotropic Viral Integration Site 1 ProteinAnimalsHypoxiaEnergy MetabolismGlycolysisHematopoietic Stem CellsMice, Inbred C57BLNeoplasm ProteinsTranscriptional ActivationHomeodomain ProteinsMiceHypoxia-Inducible Factor 1, alpha SubunitStem Cell NicheMetabolomics
Funding
- Welch Foundation
- American Heart Association
Citations
1,071
FWCI
20.54
field-weighted impact
References
62
Percentile
100%
vs. same field & year
Citations per year
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References
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The EMBO Journal · 1998 · 1,593 citations
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.
The Journal of Experimental Medicine · 1996 · 2,896 citations
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