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Incidence of Adverse Drug Reactions in Hospitalized Patients

JAMA · 1998 · Vol. 279(15) · pp. 1200–1200
Jason LazarouBruce PomeranzPaul Corey

Abstract

The incidence of serious and fatal ADRs in US hospitals was found to be extremely high. While our results must be viewed with circumspection because of heterogeneity among studies and small biases in the samples, these data nevertheless suggest that ADRs represent an important clinical issue.

Pharmacovigilance and Adverse Drug ReactionsPharmaceutical Practices and Patient OutcomesPharmaceutical studies and practicesMedicineIncidence (geometry)Drug reactionConfidence intervalPediatricsDrugEmergency medicineAdverse drug reactionInternal medicinePharmacology

MeSH terms

Data CollectionHospitalsHumansIatrogenic DiseaseInpatientsProspective StudiesUnited StatesIncidenceLinear ModelsHealth Care SurveysDrug-Related Side Effects and Adverse Reactions
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References
Relationship between medication errors and adverse drug events
Journal of General Internal Medicine · 1995 · 982 citations
A random‐effects regression model for meta‐analysis
Statistics in Medicine · 1995 · 905 citations
Fundamentals of Biostatistics.
Annals of Internal Medicine · 1969 · 4,606 citations
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