article Open AccessTop 10% cited
The Mechanism of Uptake of Biodegradable Microparticles in Caco-2 Cells Is Size Dependent
Pharmaceutical Research · 1997 · Vol. 14(11) · pp. 1568–1573
Manisha P. Desai✉(University of Michigan–Ann Arbor)Vinod Labhasetwar(University of Michigan–Ann Arbor)Elke Walter(University of Michigan–Ann Arbor)Robert J. Levy(Michigan Medicine)Gordon L. Amidon(University of Michigan–Ann Arbor)
Nanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsInhalation and Respiratory Drug DeliveryMicroparticleChemistryPolylactic acidParticle sizeChromatographyPLGAMicrosphereConfocal microscopyFluorescenceBiophysics
MeSH terms
Polylactic Acid-Polyglycolic Acid CopolymerAnimalsCattleCell Membrane PermeabilityHumansIntestinal AbsorptionMicrospheresModels, BiologicalParticle SizePolyglycolic AcidPolymersSerum Albumin, BovineMicroscopy, ConfocalCaco-2 CellsLactic Acid
Citations
853
FWCI
7.62
field-weighted impact
References
33
Percentile
98%
vs. same field & year
Citations per year
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References
Gastrointestinal Uptake of Biodegradable Microparticles: Effect of Particle Size
Pharmaceutical Research · 1996 · 930 citations
Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
Biochemical and Biophysical Research Communications · 1991 · 1,852 citations
Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells
Journal of Pharmaceutical Sciences · 1990 · 833 citations
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