articleTop 10% cited

Caco-2 Cell Monolayers as a Model for Drug Transport Across the Intestinal Mucosa

Pharmaceutical Research · 1990 · Vol. 7(9) · pp. 902–910

Allen R. Hilgers✉(W.E. Upjohn Institute for Employment Research)Robert A. ConradiPhilip S. Burton

Neuropeptides and Animal Physiology Pancreatic function and diabetes Advanced Drug Delivery SystemsIntestinal mucosaCaco-2DrugChemistryPharmacologyCellBiologyMedicineBiochemistryInternal medicine

MeSH terms

AdenocarcinomaAlkaline PhosphataseBiological TransportCell Membrane PermeabilityColonic NeoplasmsHumansHydrogen-Ion ConcentrationIntestinal MucosaPolyethylene GlycolsTumor Cells, Cultured

Citations

579

FWCI

3.53

field-weighted impact

References

Percentile

95%

vs. same field & year

Citations per year

Cited by

Caco‐2 versus Caco‐2/HT29‐MTX Co‐cultured Cell Lines: Permeabilities Via Diffusion, Inside‐ and Outside‐Directed Carrier‐Mediated Transport

Journal of Pharmaceutical Sciences · 2000 · 464 citations

Caco-2 monolayers in experimental and theoretical predictions of drug transport1PII of original article: S0169-409X(96)00415-2. The article was originally published in Advanced Drug Delivery Reviews 22 (1996) 67–84.1

Advanced Drug Delivery Reviews · 2001 · 1,524 citations

MDCK (Madin-Darby Canine Kidney) Cells: A Tool for Membrane Permeability Screening

Journal of Pharmaceutical Sciences · 1999 · 960 citations

References

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

Gastroenterology · 1989 · 2,193 citations

THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY

The Journal of Cell Biology · 1963 · 24,983 citations

Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.