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Metformin kinetics in healthy subjects and in patients with diabetes mellitus.
British Journal of Clinical Pharmacology · 1981 · Vol. 12(2) · pp. 235–246
GT Tucker✉(Royal Hallamshire Hospital)Clare E. Casey(Royal Hallamshire Hospital)PJ PhillipsHenry Connor(Royal Hallamshire Hospital)Ward Jd(Royal Hallamshire Hospital)HF Woods(Royal Hallamshire Hospital)
Abstract
The kinetics of metformin were studied after i.v. and oral administration in four healthy subjects and after oral administration in twelve maturity onset (Type II) diabetic patients.
Diet and metabolism studiesMetabolism, Diabetes, and CancerDiabetes Treatment and ManagementMetforminCitationLactic acidosisMedicineDiabetes mellitusLibrary scienceInternal medicineComputer scienceEndocrinology
MeSH terms
Administration, OralAdultAgedDiabetes MellitusFemaleHumansInjections, IntravenousIntestinal AbsorptionKineticsMaleMetforminMiddle Aged
Citations
492
FWCI
0.64
field-weighted impact
References
19
Percentile
64%
vs. same field & year
Citations per year
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References
New Method for Calculating the Intrinsic Absorption Rate of Drugs
Journal of Pharmaceutical Sciences · 1968 · 463 citations
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