reviewTop 1% cited
CD4+CD25+ suppressor T cells: more questions than answers
Nature reviews. Immunology · 2002 · Vol. 2(6) · pp. 389–400
Ethan M. Shevach✉(National Institute of Allergy and Infectious Diseases)
T-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesImmune Cell Function and InteractionIL-2 receptorSuppressorImmunogenicityImmunologyImmune systemDownregulation and upregulationBiologyCell biologyImmune tolerancePopulation
MeSH terms
AbataceptAnimalsAntigen-Presenting CellsAntigens, DifferentiationHomeostasisHumansImmune ToleranceLymphocyte ActivationThymus GlandReceptors, Interleukin-2Antigens, CDCD4 AntigensCytokinesTransforming Growth Factor betaModels, Immunological
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References
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
Nature Immunology · 2001 · 1,632 citations
CD4+CD25high Regulatory Cells in Human Peripheral Blood
The Journal of Immunology · 2001 · 1,845 citations
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
Nature Immunology · 2010 · 5,839 citations
Human CD4+CD25+ thymocytes and peripheral T cells have immune suppressive activityin vitro
European Journal of Immunology · 2001 · 487 citations
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