articleTop 1% cited
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
Nature Immunology · 2000 · Vol. 1(6) · pp. 489–495
Nils Holler✉(University of Lausanne)Rossana Zaru(University of Lausanne)Olivier Micheau(University of Lausanne)Margot Thome(University of Lausanne)Antoine Attinger(University of Lausanne)Salvatore Valitutti(University of Lausanne)Jean-Luc Bodmer(University of Lausanne)Pascal Schneider(University of Lausanne)Brian Seed(Massachusetts General Hospital)Jürg Tschopp(University of Lausanne)
Cell death mechanisms and regulationPhagocytosis and Immune RegulationNF-κB Signaling PathwaysFADDDeath domainCell biologyProgrammed cell deathFas ligandApoptosisCaspaseCaspase 8Tumor necrosis factor alphaBiology
MeSH terms
AnimalsCarrier ProteinsHumansMembrane GlycoproteinsMice, Inbred BALB CModels, BiologicalNecrosisProteinsT-LymphocytesTumor Necrosis Factor-alphaSignal TransductionCell DeathApoptosisfas ReceptorJurkat Cells
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References
Mitochondrial control of cell death
Nature Medicine · 2000 · 3,102 citations
More than one way to die: apoptosis, necrosis and reactive oxygen damage
Oncogene · 1999 · 863 citations
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
British Journal of Cancer · 1972 · 15,557 citations
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Cell · 1998 · 4,423 citations
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