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MUSCLE: a multiple sequence alignment method with reduced time and space complexity

BMC Bioinformatics · 2004 · Vol. 5(1) · pp. 113–113
R. C. Edgar

Abstract

MUSCLE offers a range of options that provide improved speed and / or alignment accuracy compared with currently available programs. MUSCLE is freely available at http://www.drive5.com/muscle.

Genomics and Phylogenetic StudiesMachine Learning in BioinformaticsGlycosylation and Glycoproteins ResearchSequence (biology)Computational biologySequence alignmentComputer scienceMultiple sequence alignmentAlignment-free sequence analysisSpace (punctuation)DNA microarrayBiologyBioinformatics

MeSH terms

PhylogenySoftwareSoftware DesignTime FactorsCluster AnalysisSequence AlignmentComputational Biology
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References
The neighbor-joining method: a new method for reconstructing phylogenetic trees.
Molecular Biology and Evolution · 1987 · 60,290 citations
The Protein Data Bank
Nucleic Acids Research · 2000 · 39,191 citations
MUSCLE: multiple sequence alignment with high accuracy and high throughput
Nucleic Acids Research · 2004 · 45,964 citations
Inferring Phylogenies.
The American Journal of Human Genetics · 2004 · 3,057 citations
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