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Giorgio Trinchieri

The Wistar InstituteORCID https://orcid.org/0000-0001-5892-7464

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Impact (2-yr)

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Top Publications

Interleukin-12 and the regulation of innate resistance and adaptive immunity

Nature reviews. Immunology20033,858 citationsFirst authorCorresponding

Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity

Annual Review of Immunology19952,419 citationsFirst authorCorresponding

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.

The Journal of Experimental Medicine19891,968 citations

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

The Journal of Experimental Medicine19931,686 citations

Plasmacytoid dendritic cells in immunity

Nature Immunology20041,636 citations

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

The Journal of Immunology19951,542 citations

Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice

European Journal of Immunology1995475 citationsCorresponding

Giorgio Trinchieri · Scinovex