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David Botstein

Howard Hughes Medical InstituteORCID https://orcid.org/0000-0001-9499-4883

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Publications

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Citations

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Impact (2-yr)

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Top Publications

Gene Ontology: tool for the unification of biology

Nature Genetics200043,975 citations

Cluster analysis and display of genome-wide expression patterns

Proceedings of the National Academy of Sciences199816,353 citationsCorresponding

Molecular portraits of human breast tumours

Nature200016,173 citations

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Proceedings of the National Academy of Sciences200110,888 citations

Repeated observation of breast tumor subtypes in independent gene expression data sets

Proceedings of the National Academy of Sciences20035,398 citations

Mapping mendelian factors underlying quantitative traits using RFLP linkage maps.

Genetics19895,300 citations

Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes

Molecular Biology of the Cell20004,901 citations

Comprehensive Identification of Cell Cycle–regulated Genes of the Yeast<i>Saccharomyces cerevisiae</i>by Microarray Hybridization

Molecular Biology of the Cell19984,786 citations

Missing value estimation methods for DNA microarrays

Bioinformatics20014,180 citations

Exploring the new world of the genome with DNA microarrays

Nature Genetics19992,420 citations

Systematic variation in gene expression patterns in human cancer cell lines

Nature Genetics20002,090 citations

Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors

Molecular Biology of the Cell20021,593 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

Gene19871,151 citations

Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experiments

Gene1979961 citationsFirst authorCorresponding

Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds

PLoS Biology2004953 citations

Gene Expression Patterns in Human Liver Cancers

Molecular Biology of the Cell2002861 citations

Coordination of Growth Rate, Cell Cycle, Stress Response, and Metabolic Activity in Yeast

Molecular Biology of the Cell2007592 citations

Expression of Cytokeratins 17 and 5 Identifies a Group of Breast Carcinomas with Poor Clinical Outcome

American Journal Of Pathology2002563 citations

Genomic Expression Responses to DNA-damaging Agents and the Regulatory Role of the Yeast ATR Homolog Mec1p

Molecular Biology of the Cell2001545 citations

Different Gene Expression Patterns in Invasive Lobular and Ductal Carcinomas of the Breast

Molecular Biology of the Cell2004459 citations