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G

George F. Koob

Scripps HealthORCID https://orcid.org/0009-0002-9857-4493

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Impact (2-yr)

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Top Publications

Neurocircuitry of Addiction

Neuropsychopharmacology20095,148 citationsFirst authorCorresponding

Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants.

Journal of Pharmacology and Experimental Therapeutics1993748 citations

Alcoholism: Allostasis and Beyond

Alcoholism Clinical and Experimental Research2003743 citationsFirst authorCorresponding

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens

Pharmacology Biochemistry and Behavior1980726 citations

Drug dependence: stress and dysregulation of brain reward pathways

Drug and Alcohol Dependence1998705 citations

Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats

Psychopharmacology1984652 citations

Effects of Moderate Alcohol Consumption on the Central Nervous System*

Alcoholism Clinical and Experimental Research1998637 citations

Animal models of drug craving

Psychopharmacology1993566 citations

Neurocircuitry Targets in Ethanol Reward and Dependence

Alcoholism Clinical and Experimental Research1998563 citationsFirst authorCorresponding

Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems

Psychopharmacology1982558 citations

The Development and Maintenance of Drug Addiction

Neuropsychopharmacology2013553 citations

Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty

Life Sciences1982539 citations

Addiction as a stress surfeit disorder

Neuropharmacology2013485 citationsFirst authorCorresponding

Neurobiological substrates for the dark side of compulsivity in addiction

Neuropharmacology2008451 citationsFirst authorCorresponding

Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats

Pharmacology Biochemistry and Behavior1982446 citations

The dark side of emotion: The addiction perspective

European Journal of Pharmacology2015442 citationsFirst authorCorresponding

Increased Ethanol Self‐Administration and Anxiety‐Like Behavior During Acute Ethanol Withdrawal and Protracted Abstinence: Regulation by Corticotropin‐Releasing Factor

Alcoholism Clinical and Experimental Research2002390 citations

Enhanced Alcohol Self‐Administration after Intermittent Versus Continuous Alcohol Vapor Exposure

Alcoholism Clinical and Experimental Research2004351 citationsCorresponding

Intra‐amygdala Muscimol Decreases Operant Ethanol Self‐administration in Dependent Rats

Alcoholism Clinical and Experimental Research1996350 citations

Heterogeneity of Alcohol Use Disorder: Understanding Mechanisms to Advance Personalized Treatment

Alcoholism Clinical and Experimental Research2015320 citations