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Laurent Salphati

Cancer Research UK

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Top Publications

The Identification of 2-(1<i>H</i>-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-<i>d</i>]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer

Journal of Medicinal Chemistry2008741 citations

GDC-0449—A potent inhibitor of the hedgehog pathway

Bioorganic & Medicinal Chemistry Letters2009385 citations

Laurent Salphati · Scinovex