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Brinda Ravikumar

Addenbrooke's Hospital

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Impact (2-yr)

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Top Publications

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Nature Genetics20042,306 citationsFirst authorCorresponding

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

Human Molecular Genetics20021,084 citationsFirst authorCorresponding

Rapamycin alleviates toxicity of different aggregate-prone proteins

Human Molecular Genetics2005655 citations

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

Cell Death and Differentiation2008580 citations