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Carl H. June

University of PennsylvaniaORCID https://orcid.org/0000-0003-0241-3557
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Top Publications

Delivery technologies for cancer immunotherapy
Nature Reviews Drug Discovery20192,556 citations
T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia
Science Translational Medicine20112,388 citationsCorresponding
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
Science Translational Medicine20171,724 citations
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
Science Translational Medicine20151,707 citations
The CD28 Signaling Pathway Regulates Glucose Metabolism
Immunity20021,417 citations
SHP-1 and SHP-2 Associate with Immunoreceptor Tyrosine-Based Switch Motif of Programmed Death 1 upon Primary Human T Cell Stimulation, but Only Receptor Ligation Prevents T Cell Activation
The Journal of Immunology20041,218 citations
Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition
Clinical Cancer Research2016917 citationsCorresponding
CD33-specific chimeric antigen receptor T cells exhibit potent preclinical activity against human acute myeloid leukemia
Leukemia2015425 citations
A versatile system for rapid multiplex genome-edited CAR T cell generation
Oncotarget2017396 citations