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David C. Rubinsztein

University of CambridgeORCID https://orcid.org/0000-0001-5002-5263
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Top Publications

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Cell Death and Differentiation20186,293 citations
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Nature Genetics20134,605 citations
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
Nature Genetics20093,381 citations
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Nature Genetics20193,124 citations
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
Cell Death and Differentiation20112,411 citations
New insights into the genetic etiology of Alzheimer’s disease and related dementias
Nature Genetics20222,354 citations
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
Nature Genetics20042,306 citations
Molecular definitions of autophagy and related processes
The EMBO Journal20171,585 citations
Autophagy in major human diseases
The EMBO Journal20211,474 citations
Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease
PLoS ONE20141,405 citations
Autophagy in malignant transformation and cancer progression
The EMBO Journal20151,149 citations
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Cell Death and Differentiation20141,008 citations
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes
Cell Death and Differentiation2009674 citations
Rapamycin alleviates toxicity of different aggregate-prone proteins
Human Molecular Genetics2005655 citations
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
Cell Death and Differentiation2008580 citations
David C. Rubinsztein · Scinovex