Comparative evaluation of hematobiochemical parameters in cats receiving intramuscular atropine-tiletamine-zolazepam and dexmedetomidine-ketamine-butorphanol anaesthetic combinations

Abstract

Ovariohysterectomy is one of the most common operative procedures performed in female cats. In present clinical study twelve (N=12) non-descript female cats were divided in two equal groups regardless of age and body weight to evaluate various haematobiochemical parameters. Cats in group I were anaesthetized using single intramuscular administration of Atropine-Tiletamine-Zolazepam (A-TZ) whereas cats of group II were anaesthetized using Dexmedetomidine-Butorphanol-Ketamine (DBK) intramuscularly and each cat operated for elective ovariohysterectomy. Blood samples were taken before anaesthesia, 10 minutes after anaesthesia, 30 minutes after anaesthesia and after recovery of anaesthesia to evaluate hematobiochemical parameters. Statistically significant reduction was noted in values of Hb and PCV in group I; while group II showed statistically significant changes in TEC, PCV, Platelet and serum creatinine. However, various haemato-biochemical parameters in present study fluctuated throughout the observation period but remained within normal reference limits. Based on present clinical study it was concluded that atropine-tiletamine-zolazepam and dexmedetomidine-butorphanol-ketamine administrated safely in cats.