Molecular detection of multidrug resistant Mycobacterium Tuberculosis Complex (MTBC) in extra-pulmonary and pulmonary infections in Bauchi LGA, Bauchi State

Abstract

Multidrug Resistant Tuberculosis has lately become a major public health problem that threatens the current achievement in Tuberculosis care and control worldwide, Multidrug Resistant Tuberculosis is a form of tuberculosis that is resistant to two primary drugs (Rifampicin and Isoniazid). This study was designed to identify TB and detect resistance to rifampicin using Genexpert system. MDR-TB was investigated in 250 suspects within the age bracket of 1-90years from 5 clinics in Bauchi. The overall prevalence of tuberculosis/RIF resistant detected was 3.2%, males had the highest prevalence with (2.0%) those at the age bracket of 16-30yrs and 31-45yrs having the high percentages. MDR-TB is not prevalent in Bauchi LGA. Because overall prevalence rate was low. There is need to do more on clinical management to totally eradicate the infection from the area, also, health care providers to encourage early and correct diagnosis, detection and treatments to all TB patients.