Hyperthermic intraperitoneal chemotherapy and cytoreductive surgery patient perioperative management (CRS-HIPEC): The part temperature, fluid, and acid-base management play

Abstract

Case Report: A 32-year-old female patient was diagnosed with bilateral ovarian adenocarcinoma accompanied by peritoneal carcinomatosis. To manage her condition, she underwent cytoreductive surgery (CRS) with successful tumor resection on August 11, 2019. Following this procedure, she was admitted for hyperthermic intraperitoneal chemotherapy (HIPEC), which was performed under general anesthesia along with a noncontinuous epidural block to assist with pain control. During the HIPEC procedure, careful intraoperative fluid management was implemented to address significant fluid shifts and third-space losses resulting from the extensive surgical intervention. A combination of crystalloids, colloids, and blood products was administered to ensure proper volume replacement and maintain hemodynamic stability. Additionally, strict monitoring and regulation of electrolyte levels and acid-base balance were essential to minimize the risk of complications. After surgery, the patient was transferred to the intensive care unit (ICU) for close monitoring and ongoing supportive care. Her recovery progressed smoothly without major complications. Over the following days, she maintained stable vital signs, exhibited adequate organ function, and showed steady clinical improvement. By the 10th postoperative day, she had met the criteria for hospital discharge and was released with a follow-up care plan in place to support her continued recovery and long-term health management.