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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
Advanced Drug Delivery Reviews · 2012 · Vol. 64 · pp. 4–17
Christopher A. Lipinski✉(Pfizer (United States))Franco Lombardo(Pfizer (United States))Beryl W. Dominy(Pfizer (United States))Paul J. Feeney(Pfizer (United States))
Crystallization and Solubility StudiesAnalytical Chemistry and ChromatographyPharmacogenetics and Drug MetabolismSolubilityDrug discoveryThermodynamicsChemistryPermeability (electromagnetism)PermeationWork (physics)Hildebrand solubility parameterComputational chemistryOrganic chemistry
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