Evaluation of the diagnostic and prognostic value of preoperative inflammatory parameters in testicular tumors

Abstract

Objective: We aimed to investigate neutrophil lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) values can be used as predictors of a tumor marker or disease progression in patients with testicular tumors. Materials and Methods: A retrospective analysis of 142 patients undergoing orchiectomy in our center was performed. Sixty-six patients with malignant testicular tumor pathology were included in the study group and 14 patients with benign orchiectomy pathology were included in the control group Preoperative inflammatory parameters of both groups were compared. Results: Mean ages were 30 ± 4 (26, 34 IQR) years in the study group and 30 ± 7 years (23, 41 IQR) in the control group. A total of 66 testiculer tumor patients had a higher neutrophile and NLR compared to the control group (P=0.03, p=0.005, respectively). LnNLR levels [95% CI: 4.90 (1.55, 15.43), P= 0.007] were significantly associated with testicular tumor in logistic regression analysis. Conclusions: As a result of our study; preoperative NLR can be used as a value that supports other diagnostic methods rather than evaluating the progression of the disease in testicular tumors.