Histopathological spectrum of endometrial biopsies in abnormal uterine bleeding: A one year experience in a tertiary care centre

Abstract

Background: Abnormal uterine bleeding (AUB) shows spectrum of patterns on histopathology and pathologist plays a very vital role in reporting of endometrial biopsies and helps in differentiating non-neoplastic lesion from neoplastic lesions, early detection of the precursor lesions and exclusion of malignancy. The aim of this study is to study the spectrum of endometrial patterns in women with AUB and to correlate it with the different age groups. Materials and Methods: 272 samples of endometrial biopsies with AUB were received from the gynaecology department, processed and stained with hematoxylin & eosin and subjected to histopathological examination. Results: The peak incidence is observed in the age group of 41-50 years. The most common histomorphological pattern is proliferative pattern. 66 cases (24.26%) show endometrial hyperplasia out of which 8cases show atypia. 6 cases of endometrial carcinoma were reported and most of them were present in postmenopausal age. Pill endometrium and chronic endometritis were not reported in postmenopausal age group and all 3 cases of atrophic endometrium were reported in postmenopausal age group. Conclusion: AUB significantly affects the quality life of women and leads to anemia. Hence histopathological examination should be considered which plays a critical role in early diagnosis of endometrial pathology and to provide appropriate gynaecological management.