article Open AccessTop 10% cited
SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects
Nature Structural & Molecular Biology · 2020 · Vol. 27(8) · pp. 763–767
Antoni G. Wrobel✉(The Francis Crick Institute)D.J. Benton(The Francis Crick Institute)Pengqi Xu(Sun Yat-sen University)Chloë Roustan(The Francis Crick Institute)Stephen R. Martin(The Francis Crick Institute)Peter B. Rosenthal(The Francis Crick Institute)J.J. Skehel(The Francis Crick Institute)S.J. Gamblin(The Francis Crick Institute)
SARS-CoV-2 and COVID-19 ResearchViral Infections and Outbreaks ResearchViral gastroenteritis research and epidemiologyFurinGlycoproteinCleavage (geology)VirusBiologyReceptorSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCell biologyCoronavirus disease 2019 (COVID-19)
MeSH terms
Protein Conformation, alpha-HelicalProtein Conformation, beta-StrandBetacoronavirusAngiotensin-Converting Enzyme 2COVID-19SARS-CoV-2AnimalsBinding SitesChiropteraHumansPeptidyl-Dipeptidase AModels, MolecularPneumonia, ViralProtein BindingReceptors, Virus
Funding
- Wellcome
- Wellcome Trust
- Francis Crick Institute
- Cancer Research UK
- Sun Yat-sen University
- Medical Research Council
- Sanming Project of Medicine in Shenzhen
Citations
619
FWCI
13.26
field-weighted impact
References
36
Percentile
99%
vs. same field & year
Citations per year
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Journal of Molecular Biology · 2003 · 2,570 citations
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
Nature Methods · 2017 · 10,267 citations
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
Nature Methods · 2017 · 8,716 citations
A new coronavirus associated with human respiratory disease in China
Nature · 2020 · 12,814 citations
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Nature · 2020 · 23,190 citations
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Science · 2020 · 9,712 citations
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