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Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

Biomaterials · 2017 · Vol. 150 · pp. 137–149
Tian TianHuixin ZhangChunpeng HeSong FanYanliang ZhuCui QiNing‐Ping HuangZhongdang XiaoZuhong LuBakhos A. TannousJun Gao
Extracellular vesicles in diseaseRNA Interference and Gene DeliveryMicroRNA in disease regulationMicrovesiclesExosomeDrug deliveryPharmacologyIschemiaBlood–brain barrierMedicineMaterials scienceDrugNanotechnology

MeSH terms

AnimalsCurcuminDisease Models, AnimalHeLa CellsHumansInjections, IntravenousMaleMice, Inbred C57BLPeptidesPharmaceutical VehiclesInfarction, Middle Cerebral ArteryStrokeCell Line, TumorMiceExosomes

Funding

  • National Natural Science Foundation of China
  • Government of Jiangsu Province
  • Natural Science Foundation of Jiangsu Province
Citations
1,114
FWCI
24.40
field-weighted impact
References
75
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100%
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References
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Exosomes as drug delivery vehicles for Parkinson's disease therapy
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Exosomes – vesicular carriers for intercellular communication
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The immunology of stroke: from mechanisms to translation
Nature Medicine · 2011 · 2,484 citations
Heart Disease and Stroke Statistics—2016 Update
Circulation · 2015 · 6,623 citations
Extracellular vesicles for drug delivery
Advanced Drug Delivery Reviews · 2016 · 1,204 citations
The biology and function of exosomes in cancer
Journal of Clinical Investigation · 2016 · 1,880 citations
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