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Recent progress in transition-metal-catalyzed enantioselective indole functionalizations

Organic & Biomolecular Chemistry · 2017 · Vol. 15(17) · pp. 3550–3567
Jing-Biao ChenYi‐Xia Jia

Abstract

Numerous efficient synthetic methods for enantioselective indole functionalizations have emerged in recent years. This review summarizes the major achievements in the transition-metal-catalyzed enantioselective indole functionalization reactions since 2010 and focuses on C-C bond formation processes, including alkylations, arylations, cycloaddition reactions, and other reactions. It intends to give a compendious overview of the significant progress achieved in this area.

Catalytic C–H Functionalization MethodsAsymmetric Synthesis and CatalysisAsymmetric Hydrogenation and CatalysisEnantioselective synthesisIndole testCatalysisChemistryStereochemistryOrganic chemistry

MeSH terms

AlkylationCatalysisIndolesStereoisomerismTransition Elements

Funding

  • National Natural Science Foundation of China
  • Natural Science Foundation of Zhejiang Province
Citations
284
FWCI
15.35
field-weighted impact
References
181
Percentile
100%
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Citations per year
References
Recent advances in indole syntheses: New routes for a classic target
Organic & Biomolecular Chemistry · 2011 · 365 citations
A review on recent developments of indole-containing antiviral agents
European Journal of Medicinal Chemistry · 2014 · 859 citations
Indole synthesis: a review and proposed classification
Tetrahedron · 2011 · 725 citations
Indole synthesis – something old, something new
Chemical Science · 2012 · 641 citations
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