article Open AccessTop 1% cited
Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity
Cell Death and Differentiation · 2016 · Vol. 24(2) · pp. 357–370
William W. Du✉(Sunnybrook Research Institute)Ling Fang(Union Hospital)Weining Yang(Health Sciences Centre)Nan Wu(Health Sciences Centre)Faryal Mehwish Awan(Health Sciences Centre)Zhenguo Yang(Sunnybrook Health Science Centre)Burton B. Yang(Health Sciences Centre)
Circular RNAs in diseasesCancer-related molecular mechanisms researchRNA Research and SplicingFOXO3Gene silencingApoptosismicroRNAPumaCompeting endogenous RNADownregulation and upregulationEctopic expressionMdm2Cell biology
MeSH terms
Forkhead Box Protein O3RNA, CircularAnimalsBreast NeoplasmsCell LineCisplatinDoxorubicinFemaleHumansHydrogen PeroxideNucleic Acid ConformationRNASurvival RateTumor Suppressor Protein p53Apoptosis
Funding
- Heart and Stroke Foundation of Canada
- National Natural Science Foundation of China
- Canadian Institutes of Health Research
Citations
848
FWCI
22.98
field-weighted impact
References
29
Percentile
100%
vs. same field & year
Citations per year
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References
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Nature Structural & Molecular Biology · 2015 · 3,018 citations
Detecting and characterizing circular RNAs
Nature Biotechnology · 2014 · 2,893 citations
Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation
Cell Reports · 2014 · 1,070 citations
Circular Intronic Long Noncoding RNAs
Molecular Cell · 2013 · 2,227 citations
Natural RNA circles function as efficient microRNA sponges
Nature · 2013 · 8,387 citations
Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily
Genomics · 1998 · 353 citations
Mfold web server for nucleic acid folding and hybridization prediction
Nucleic Acids Research · 2003 · 13,453 citations
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