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Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance

Frontiers in Microbiology · 2016 · Vol. 7 · pp. 1538–1538
Sushanto GoudaGitishree DasSandeep K. SenHan‐Seung ShinJayanta Kumar Patra

Abstract

Endophytes are an endosymbiotic group of microorganisms that colonize in plants and microbes that can be readily isolated from any microbial or plant growth medium. They act as reservoirs of novel bioactive secondary metabolites, such as alkaloids, phenolic acids, quinones, steroids, saponins, tannins, and terpenoids that serve as a potential candidate for antimicrobial, anti-insect, anticancer and many more properties. While plant sources are being extensively explored for new chemical entities for therapeutic purposes, endophytic microbes also constitute an important source for drug discovery. This review aims to comprehend the contribution and uses of endophytes as an impending source of drugs against various forms of diseases and other possible medicinal use.

Plant tissue culture and regenerationPlant-Microbe Interactions and ImmunityPlant and fungal interactionsAntimicrobialBiologyTerpenoidDrug discoveryTraditional medicineMedicinal plantsTreasureBiotechnologyBotanyMicrobiology
Citations
833
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21.24
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References
91
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References
The plant microbiome
Genome biology · 2013 · 1,298 citations
Arbuscular mycorrhiza: the mother of plant root endosymbioses
Nature Reviews Microbiology · 2008 · 2,104 citations
Antibacterial action of several tannins against Staphylococcus aureus
Journal of Antimicrobial Chemotherapy · 2001 · 797 citations
Going back to the roots: the microbial ecology of the rhizosphere
Nature Reviews Microbiology · 2013 · 3,652 citations
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