reviewTop 1% cited
The biology and function of fibroblasts in cancer
Nature reviews. Cancer · 2016 · Vol. 16(9) · pp. 582–598
Raghu Kalluri✉(The University of Texas MD Anderson Cancer Center)
Cancer Cells and MetastasisFibroblast Growth Factor ResearchCancer Research and TreatmentsCancer-Associated FibroblastsCancer cellExtracellular matrixBiologyTumor microenvironmentReprogrammingCancerPopulationCancer researchContext (archaeology)
MeSH terms
Cell DifferentiationExtracellular MatrixFibroblastsFibrosisForecastingHumansNeoplasm MetastasisNeoplasm ProteinsNeoplasmsNeovascularization, PathologicWound HealingCytokinesStromal CellsDisease ProgressionDrug Resistance, Neoplasm
Citations
4,144
FWCI
119.62
field-weighted impact
References
246
Percentile
100%
vs. same field & year
Citations per year
Cited by
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
The Journal of Experimental Medicine · 2017 · 2,400 citations
In search of definitions: Cancer‐associated fibroblasts and their markers
International Journal of Cancer · 2019 · 722 citations
Cancer-associated fibroblasts induce PDL1+ neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma
Cell Death and Disease · 2018 · 384 citations
The Role of the Extracellular Matrix and Its Molecular and Cellular Regulators in Cancer Cell Plasticity
Frontiers in Oncology · 2018 · 375 citations
Macrophages as regulators of tumour immunity and immunotherapy
Nature reviews. Immunology · 2019 · 2,440 citations
A framework for advancing our understanding of cancer-associated fibroblasts
Nature reviews. Cancer · 2020 · 3,630 citations
Tumor Microenvironment: Extracellular Matrix Alterations Influence Tumor Progression
Frontiers in Oncology · 2020 · 302 citations
Concepts of extracellular matrix remodelling in tumour progression and metastasis
Nature Communications · 2020 · 2,129 citations
References
EMT, CTCs and CSCs in tumor relapse and drug-resistance
Oncotarget · 2015 · 462 citations
Inflammation and cancer
Nature · 2002 · 14,998 citations
Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
Cellular and Molecular Life Sciences · 1971 · 1,467 citations
Cancer-Associated Fibroblasts as Another Polarized Cell Type of the Tumor Microenvironment
Frontiers in Oncology · 2014 · 416 citations
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
Nature Cell Biology · 2007 · 1,544 citations
Myofibroblasts in human granulation tissue
Human Pathology · 1974 · 384 citations
Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
Cancer Cell · 2014 · 1,973 citations
New functions for the matrix metalloproteinases in cancer progression
Nature reviews. Cancer · 2002 · 6,034 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.